Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
| Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
| Upregulated in class | truncNotch |
| GeneSet | HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS, PYRUVATE DEHYDROGENASE, TCA, AND GLYOXYLATE BYPASS |
| Enrichment Score (ES) | 0.73724246 |
| Normalized Enrichment Score (NES) | 1.6314688 |
| Nominal p-value | 0.0016393443 |
| FDR q-value | 0.048553355 |
| FWER p-Value | 0.483 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PKM2 | 6520403 70500 | 8 | 11.751 | 0.1418 | Yes | ||
| 2 | ALDOA | 6290672 | 14 | 10.281 | 0.2661 | Yes | ||
| 3 | PFKL | 6200167 | 205 | 5.841 | 0.3266 | Yes | ||
| 4 | PFKM | 1990156 5720168 | 383 | 4.761 | 0.3747 | Yes | ||
| 5 | TPI1 | 1500215 2100154 | 397 | 4.690 | 0.4308 | Yes | ||
| 6 | ENO3 | 5270136 | 448 | 4.550 | 0.4832 | Yes | ||
| 7 | MDH2 | 1850601 | 514 | 4.312 | 0.5319 | Yes | ||
| 8 | FBP1 | 1470762 | 517 | 4.307 | 0.5839 | Yes | ||
| 9 | PGAM1 | 2570133 | 776 | 3.540 | 0.6129 | Yes | ||
| 10 | ENO1 | 5340128 | 1000 | 3.040 | 0.6377 | Yes | ||
| 11 | SDHC | 3140347 6100156 | 1035 | 2.973 | 0.6719 | Yes | ||
| 12 | PGAM2 | 3610605 | 1240 | 2.639 | 0.6928 | Yes | ||
| 13 | SDHD | 2570128 | 1664 | 2.059 | 0.6950 | Yes | ||
| 14 | ACO1 | 50114 | 1742 | 1.982 | 0.7148 | Yes | ||
| 15 | PGK1 | 1570494 630300 | 1768 | 1.961 | 0.7372 | Yes | ||
| 16 | SDHB | 3120398 4780113 3710435 | 2156 | 1.530 | 0.7349 | No | ||
| 17 | DLST | 2320722 | 2430 | 1.279 | 0.7357 | No | ||
| 18 | ACO2 | 4230600 | 2940 | 0.926 | 0.7195 | No | ||
| 19 | CS | 5080600 | 3021 | 0.868 | 0.7257 | No | ||
| 20 | IDH2 | 2680397 | 3986 | 0.438 | 0.6792 | No | ||
| 21 | GAPDHS | 2690463 | 4482 | 0.320 | 0.6564 | No | ||
| 22 | FBP2 | 1580193 | 5642 | 0.169 | 0.5960 | No | ||
| 23 | AMAC1 | 940270 | 6054 | 0.132 | 0.5755 | No | ||
| 24 | DLD | 4150403 6590341 | 6289 | 0.118 | 0.5644 | No | ||
| 25 | PDHX | 870315 | 7638 | 0.064 | 0.4926 | No | ||
| 26 | PKLR | 1170400 2470114 | 9931 | 0.016 | 0.3694 | No | ||
| 27 | ALDOB | 4730324 | 11701 | -0.014 | 0.2744 | No | ||
| 28 | SDHA | 7000056 | 12362 | -0.029 | 0.2392 | No | ||
| 29 | MDH1 | 6660358 6760731 | 12975 | -0.046 | 0.2068 | No | ||
| 30 | PGK2 | 2650091 | 13746 | -0.087 | 0.1664 | No | ||
| 31 | ALDOC | 450121 610427 | 13912 | -0.100 | 0.1587 | No | ||
| 32 | OGDH | 3840333 6350100 | 14835 | -0.265 | 0.1123 | No | ||
| 33 | SUCLA2 | 730632 1170292 | 14993 | -0.312 | 0.1076 | No | ||
| 34 | PFKP | 70138 6760040 1170278 | 15394 | -0.474 | 0.0918 | No | ||
| 35 | BPGM | 5080520 | 15449 | -0.501 | 0.0950 | No | ||
| 36 | PDHB | 70215 610086 | 15820 | -0.698 | 0.0835 | No | ||
| 37 | DLAT | 430452 | 16144 | -0.926 | 0.0774 | No | ||
| 38 | ENO2 | 2320068 | 16910 | -1.647 | 0.0561 | No | ||
| 39 | IDH1 | 1990021 | 17759 | -2.945 | 0.0461 | No |
